Fri Jun 20 2025

29 articles - From Friday Jun 13 2025 to Friday Jun 20 2025

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Guidelines

Guidelines and related publications, position statements, white papers, technical reviews, consensus statements, etc…


Meta-analysis

meta-analyses and systematic reviews


Original articles

RCT, clinical trials, retrospective studies, etc…

Am J Clin Nutr

A digital behavioral intervention to reduce sugar-sweetened beverage consumption: a randomized, controlled trial.

A digital behavioral intervention was efficacious in reducing SSB consumption among Appalachian adults and yielded high engagement and retention rates. This intervention should be evaluated in other populations with excessive SSB consumption.

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Associations of Prepregnancy Weight Change with Fetal Growth and Adverse Birth Outcomes: A Prospective Cohort Study in China.

Excessive prepregnancy weight gain was associated with accelerated fetal growth and increased macrosomia and LGA risks, whereas prepregnancy weight loss showed a sex-specific impact on SGA. The combination of high prepregnancy weight gain and excessive GWG was associated with the highest risks of macrosomia and LGA.

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Human milk oligosaccharides and Campylobacter jejuni and Campylobacter coli gastroenteritis risk in a Nicaraguan birth cohort.

Consuming high concentrations of 2'FL early in infants' lives was not protective against C. jejuni/coli gastroenteritis in this prospective birth cohort. However, high concentrations of LNnT and LSTc, and possibly LNFP-III may be associated with decreased C. jejuni/coli gastroenteritis and warrant investigation as potential supplements for C. jejuni/coli gastroenteritis prevention in chest-fed and formula-fed children. Safety testing for HMOs as supplements is needed for regions with prevalent enteric infections.

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Plant to animal protein ratio in the diet of the elderly: potential for increase and impacts on nutrient adequacy and long-term health - a diet optimization study.

Diets must be sufficiently rich in protein to ensure protein adequacy at higher requirements, with no risk of IAA inadequacy when protein intake is sufficient. For sustainability, %PP can potentially increase from the current ∼⅓ to ∼⅔ in an aging population while improving health and nutrient adequacy, provided sufficient seafood and dairy products remain. Further increases would require nutrient fortification/supplementation and/or new foods.

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Rethinking balanced food supplementation for pregnant women: time to move beyond energy and protein.

We articulate the need to carefully consider the goals of food supplementation during pregnancy, the biological mechanisms underlying effects on key outcomes, the desirability of flexibility in approaches, cost considerations, and the needs of the entire household in the context of food insecurity. We conclude that it is time to redefine the concept of balanced food supplementation for pregnant women, clarify objectives and terminology, and conduct further research relevant to the current global context.

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Inflamm Bowel Dis

A Guide to the Patient-Centric Use of Vedolizumab for Crohn's Disease.

We detail the ability of vedolizumab to achieve mucosal healing and alter disease progression and present the evidence that supports the use of vedolizumab as a first-line biologic early in the disease course in patients with CD. Finally, we address some of the perceived drawbacks of using vedolizumab in CD, including concerns about slow onset of action, impact of disease location, and exacerbation of extraintestinal manifestations.

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Comparative Predictive Utility of MM-SES-CD and SES-CD for Week 52 Endoscopic Remission in the Ileum and Colon in Crohn's Disease.

The baseline MM-SES-CD demonstrated superior predictive ability for week 52 ER compared to SES-CD across the ileum and colon. These findings support its utility in clinical trials and in routine practice for predicting long-term treatment response.

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Food Compounds Associated With Disease Activity in Inflammatory Bowel Disease.

We identified several compounds that may play a modulatory role in IBD. Further research is needed to clarify associations found in our study and validate their biological significance.

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J Crohns Colitis

A Randomized Controlled Trial Of Antibiotics Targeting Adherent And Invasive Escherichia Coli (Aiec) Vs Placebo In Crohn's Disease: The Teorem Trial.

A combination of ciprofloxacin and rifaximin was not superior to placebo to achieve endoscopic endpoints in patients with ileal CD colonized with AIEC.

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Gaps between European Crohn's Colitis Organisation quality standards of care and the real world on structure of IBD units across Europe: results from E-QUALITY survey.

Significant gaps in quality care standards remain across European IBD units. Enhanced support from ECCO, by education and position papers/guidelines may help bridge these gaps.

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Pharmacological inhibitors of the gamma-secretase enzyme complex disrupt epithelial cell function triggering colitis in mice.

In conclusion, systemic use of γ-secretase inhibitors disrupts epithelial cell function by impairing IEC differentiation and triggering gut inflammation in mice. These findings should be considered when designing future therapeutic interventions involving γ-secretase inhibitors.

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Liver Transpl

Outcomes of choledochoduodenostomy in pediatric liver transplantation.

Choledochoduodenostomy is considered a safe alternative. Biliary complications were not associated with graft loss or mortality. Post-operative biliary complications are infrequent, suggesting that CD is a suitable and possibly superior type of biliary reconstruction compared to conventional CC or CJ anastomosis.

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Pancreas

Complications Requiring Abdominal Surgery in Endoscopically Treated Patients With Pancreatic Walled-off Necrosis: Single Centre Case Series.

This study demonstrates that complications requiring abdominal surgery in patients undergoing endoscopic treatment for WON occur in one of 10 patients, intestinal ischemia being the most frequent cause of intervention.

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Gastrointestinal Burden in Patients with Pancreatic Insufficient Cystic Fibrosis Before and After Elexacaftor/Tezacaftor/Ivacaftor Use.

The reduction in constipation and non-infective gastroenteritis and colitis is important as GI symptoms are linked to the quality of life of CwCF. There remains a great clinical need to evaluate the effects of ETI on GI disorders, especially as the age of initial use of this therapy decreases, and the duration of use increases.

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scRNA-Seq and Bulk-Seq Identify Novel Markers Associated With Calcium Regulation and Immunomodulation in Acute Pancreatitis.

The comprehensive analysis of the ceRNA network identified novel genes may regulate calcium-related pathways and participate in the immunomodulation in AP. Not applicable.

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Pancreatology

A Mendelian randomization study investigating the causal effect of simvastatin consumption on pancreatitis risk.

Genetic evidence has not proven a causality between simvastatin and pancreatitis, suggesting that routine monitoring may be unnecessary.

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Perilesional branch duct dilation as a hallmark MRCP feature for differentiating high-grade PanIN from low-grade PanIN.

Perilesional BPD dilation on MRCP is a primary imaging feature for differentiating HG-PanIN, characterized by substantial interobserver agreement. While PPA on MRI is another important independent predictor, its lower interobserver agreement warrants caution. These findings highlight the diagnostic value of utilizing both MRCP and MRI in the noninvasive evaluation of suspected PanIN.

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Reviews&Editorials

Plenty of the editorials are available as full text through the publisher website using the provided link


Miscellaneous

misc publications eg case reports, tools of the trade, images of the month, etc…

Inflamm Bowel Dis

Can One Disease Hide Another?

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Dualistic Implications of Angiotensin-Converting Enzyme 2 (ACE2) Expression in Inflammatory Bowel Disease.

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Safety and Effectiveness of QingDai (Indigo naturalis) in Children With Mild-to-Moderate Ulcerative Colitis: A Short-Term 6-Week Open-Label Trial.

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Liver Transpl

Cannabis and Liver Transplant: We Need to Chill, Man.

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Creation of a new VA liver transplantation center increased access and retained care within veterans health administration.

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Does the heart whisper before the liver crashes? NT-proBNP and the Prediction of ACLF.

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Reply: Accurately predict the HCC recurrence after liver transplantation.

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Underappreciated value of imaging biomarkers in prognostication of HCC.

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Pancreatology

Advancing post ERCP pancreatitis prevention-insights from pharmacokinetics of rectal NSAIDs.

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Letters&Replies

Letters to the editors and authors’ replies

Pancreatology

A real-world analysis of second-line treatment option, Gemcitabine plus Anlotinib and anti-PD1, in advanced pancreatic cancer: A critical insight.

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Comment on "A causal relationship between distinct immune features and acute or chronic pancreatitis: Results from a Mendelian randomization analysis".

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Letter to Editor: Strengths and methodological Considerations for Predicting post-pancreatectomy acute pancreatitis.

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